Marmara Pharmaceutical Journal 2017 , Vol 21 , Issue 3
Study on the Antimicrobial Effects of Novel Thiazole Derivatives
Meral Yılmaz Cankılıç1,Leyla Yurttaş1
1Department of Biology, Faculty of Sciences, Anadolu University, 26470, Eskişehir, TURKEY
2Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470, Eskişehir, TURKEY
DOI : 10.12991/marupj.323584 In this work, six 2-[(1/4-methylimidazol/triazol/tetrazol- 2/3/5-yl)thio]-N-(4-substituted thiazol-2-yl) acetamide derivatives (2a-f) were synthesized. The antimicrobial activities of these substances were examined against some foodborne Gram positive and Gram negative test bacteria, Candida albicans, Candida glabrata, Candida krusei, and Candida parapsilosis yeasts, and some Aspergillus and Penicillium filamentous fungi species. The substances were shown considerable antimicrobial effect to tested pathogenic microorganisms. Keywords : antibacterial, antifungungal, thiazole